ED treatment (UK)

Sildenafil vs Tadalafil: Everything You Need to Know about These ED Tablets

Today, erectile dysfunction (ED) is a very common health condition in the United Kingdom. According to studies, this health condition affects roughly 50-55% of men, especially those that fall between the ages of 40 and 70 years. ED is never life-threatening in itself. However, if care isn’t taken quickly, this health condition won’t only affect your sex life. In addition, it will also result in more serious medical conditions, heart problems, and hypertension. Without adequate ED treatment (UK), you may also experience psychological trauma and lower self-esteem.


One of the most effective ED treatments (UK) involves using the best medications, such as ED treatment (UK) and tadalafil (20mg). In the rest of this post, we’ll create a Sildenafil vs Tadalafil face-off to better understand how to pick the best ED for your current health condition.

Sildenafil vs Tadalafil: How exactly do these tablets work?

Let’s start this face-off by first talking about how these two ED tablets (Sildenafil and Tadalafil) work.

●      Sildenafil (Viagra)


Sildenafil is the generic name for many brands, such as Viagra and Revatio. Viagra is an effective erectile tablet for treating ED or impotence in men. As for Revatio, it’s effective for improving men’s and women’s exercise capacity. Sildenafil Revatio also helps to treat pulmonary arterial hypertension.


Sildenafil (Viagra) works by assisting you in relaxing the muscles of the blood vessels. In addition, this medication also helps to increase blood flow to your private areas for a better erection.

●      Tadalafil (Cialis)

On the other hand, Tadalafil is a generic name for brands, such as Cialis. Like Viagra, Cialis is also very effective for ED treatment (UK). Apart from helping with sexual stimulation, Tadalafil (Cialis) works by increasing the flow of blood to your penis for a better and long-lasting erection.


Both Sildenafil (Viagra) and Tadalafil (Cialis) are oral medications for ED treatments. They fall under a drug class, which is known as phosphodiesterase 5 (PDE5) inhibitors. Other medications under this drug class include Avanafil (Stendra) and Vardenafil (Levitra).


  • Cyclic guanosine monophosphate (cGMP) is very important for a man’s erection. It’s usually produced by the enzyme guanylate cyclase, which can be activated by nitric oxide.
  • When attached by another enzyme, known as PDE5, cGMP tend to break down and become inactive. This is what causes a lack of erection in most men. To keep cGMP active, ED tablets such as Tadalafil and Sildenafil are all you need. They help in preventing the breakdown of your cGMP, which is responsible for your erection.

Sildenafil vs Tadalafil: what is the difference?

As you now know, both Sildenafil 25mg and Tadalafil 20mg are effective oral medications for treating erectile dysfunction. But here’s a quick question, what exactly is the difference between these tablets?


  • Sildenafil is the active ingredient in Viagra while Tadalafil is the active ingredient in Cialis. While Sildenafil was introduced in 1998, tadalafil came in 2003.


  • Sildenafil can start working 30 to 60 minutes after taking the medication. Its effects can always last for up to 6 hours. As for Tadalafil, you should expect it to start working 30 minutes after using the medication. Unlike Sildenafil, Tadalafil can last for up to 36 hours.


  • Both Sildenafil and Tadalafil have side effects. The side effects of Sildenafil include blurred vision, nausea, headaches, dizziness, and hot flashes. The side effects of Tadalafil include headaches, nausea, stuffy nose, muscle aches, and red face.ED treatment (UK)

Sildenafil vs Tadalafil: which Ed tablets last longer?

As earlier mentioned, Sildenafil can start working about 30 to 60 minutes after you use the erectile dysfunction medication. When it becomes active, you can always enjoy the erectile effects of this medicine for up to 6 hours.


Although Tadalafil also starts working about 30 minutes after using the medicine, its effects on your body will last longer than what Sildenafil (Viagra) offers. To be precise, Tadalafil (Cialis) can always last up to 36 hours, which is about 6 times that of sildenafil.


That said, Cialis is the preferred ED tablet for the weekend, as it can last longer than Viagra. The only problem, however, is that the more these PDE5 inhibitors last in your body, the more your body is exposed to the side effects mentioned earlier.

Sildenafil vs Tadalafil: do they have different dosages?

The simple answer is yes, both Sildenafil and Tadalafil have different dosages. Viagra’s doses include 100 mg, 50 mg, and 25 mg. You can take this medication as needed for your erectile issue.


Like Viagra, Cialis can also be taken as needed with a dose of 10mg or 20mg. However, the normal daily doses of these ED tablets are 2.5 mg and 5 mg.

Sildenafil vs Tadalafil: which one is cheaper?

Both Sildenafil and Tadalafil are two affordable oral medications for erectile dysfunction. Both medications are available in Ashcroft Pharmacy. Sildenafil (Viagra) has a starting price of £0.80 while Tadalafil (Cialis) has a starting price of £7.49.